Organic electro-scattering antenna: Wireless and multisite probing of electrical potentials with high spatial resolution

Summary

The study introduces organic electro-scattering antennas (OCEANs) for wireless, light-based probing of electrical signals with micrometer spatial resolution. OCEANs leverage the unique dependence of poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) light scattering properties on its doping level.

Highlights

• OCEANs enable wireless probing of electrical signals with micrometer spatial resolution.
• PEDOT:PSS light scattering properties depend on its doping level.
• OCEANs demonstrate millisecond time constants and exceptional long-term stability.
• Signal-to-noise ratios up to 48 were achieved in response to 100-mV stimuli.
• OCEANs unlock new readout capabilities, potentially accelerating fundamental and clinical research.
• The technology relies on the unique dependence of PEDOT:PSS light scattering properties on its doping level.
• OCEANs can be used to monitor electrical activity in biosensing applications.

Key Insights

• The OCEAN concept is based on the modulation of PEDOT:PSS light scattering properties in response to changes in its doping level, allowing for wireless probing of electrical signals.
• The technology has the potential to accelerate fundamental and clinical research by enabling the monitoring of electrical activity in biosensing applications with high spatial resolution.
• The use of OCEANs eliminates the need for individual conductive traces, allowing for a higher number of recording sites and improved spatial resolution.
• The use of PEDOT:PSS in OCEANs enables the modulation of light scattering properties in response to changes in its doping level, making it an ideal material for this application.
• The millisecond time constants and exceptional long-term stability of OCEANs make them suitable for a wide range of biosensing applications.
• The ability to monitor electrical activity with high spatial resolution using OCEANs has the potential to unlock new insights into biological processes and disease mechanisms.
• The development of OCEANs represents a significant advancement in the field of biosensing, enabling the wireless probing of electrical signals with micrometer spatial resolution.

Mindmap

Citation

Desbiolles, B., Hanna, J., Ausilio, R., Leccardi, M. A., Yu, Y., & Sarkar, D. (2024). Organic electro-scattering antenna: Wireless and multisite probing of electrical potentials with high spatial resolution. In Science Advances (Vol. 10, Issue 51). American Association for the Advancement of Science (AAAS). https://doi.org/10.1126/sciadv.adr8380